Alaabta
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
La mid ah: 4 (1H)-Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-kow;2,6-Diamino-4(1H)-pyrimidinone;2,6-Diamino-4(3H)-pyrimidinone;2,6-Diamino-4-hydroxypyrimidine;2,6-Diamino-4 -pyrimidinol;2,6-Diaminopyrimidin-4-kow;2,6-Diaminopyrimidine-4(3H)-hal;6-Aminoisocytosine;6-Hydroxy-2,4-pyrimidinediamine;NSC 44914;NSC 680818;NSC9302;
Hantida Kiimikada ee 2,4-Diamino-6-hydroxypyrimidine
● Muuqashada/ Midabka: Cadaan adag
● Cadaadiska Uumiga:0.00232mmHg at 25°C
● Meesha dhalaalaysa:285-286 °C (dac.)( shidday)
● Tusaha dib u soo celinta:1.7990 (qiyaas)
● Barta karkarinta:288.5 °C at 760 mmHg
● PKA: 10.61 ± 0.50 (La saadaaliyay)
● Barta Tooshka ah:128.3 °C
● PSA: 98.05000
● Cufnaanta:1.84 g/cm3
● LogP:0.50900
● Heerkulka Kaydinta: Ka saar heerkulka +4°C
● Xasaasi ah.:Nuur xasaasi ah
● Solubility.:DMSO (wax yar), Methanol (wax yar)
Daahirnimada/Tayada
99% *xogta alaab-qeybiyeyaasha cayriin
2,4-Diamino-6-hydroxypyrimidine *xogta alaab-qeybiyeyaasha reagent
Macluumaadka Badbaadada
● Sawirka:
Xi
● Xeerarka halista: Xi
● Bayaanada: 36/37/38
● Bayaanada Badbaadada:22-24/25-36-26
Faylasha MSDS
Faa'iido leh
● Sharaxaad: 2,4-Diamino-6-hydroxypyrimidine (DAHP) waa xushay, horjooge gaar ah ee GTP cyclohydrolase I, heerka xaddidaadda qiyaasta de novo pterin synthesis.Unugyada HUVEC, IC50 ee ka hortagga biosynthesis ee BH4 waxay ku saabsan tahay 0.3 mM.DAHP waxaa loo isticmaali karaa in si wax ku ool ah loo joojiyo wax soo saarka NO ee dhowr nooc oo unug ah.
● Wuxuu adeegsadaa: 2,4-Diamino-6-hydroxypyrimidine (DAHP) waa xakameyn gaar ah oo la xushay GTP cyclohydrolase I, heerka xaddidaadda qiyaasta de novo pterin synthesis.Unugyada HUVEC, IC50 ee ka hortagga biosynthesis ee BH4 waxay ku saabsan tahay 0.3 mM.DAHP waxa loo isticmaali karaa in si wax ku ool ah loo xakameeyo wax soo saarka NO ee noocyada kala duwan ee unugyada. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) waa iskudhis faa'iido u leh isku dhafka dabiiciga ah.
2,4-Diamino-6-hydroxypyrimidine waa iskudhis kiimiko ah oo leh caanaha molecular C4H6N4O.Waxaa caadi ahaan loo isticmaalaa sida dhexdhexaadka ah ee isku-dhafka xeryahooda kala duwan, oo ay ku jiraan daawooyinka dawooyinka iyo dheehyada. Xarunta waxay leedahay qaab dhismeedka giraanta pyrimidine oo ka kooban laba kooxood oo amino (NH2) iyo hal koox hydroxyl (OH) oo ku xiran atamka kaarboon ee kala duwan.Qaab dhismeedkani wuxuu ka dhigayaa dhismo isku dhafan oo loogu talagalay isku-dhafka molecules-ka adag.2,4-Diamino-6-hydroxypyrimidine waxaa lagu heli karaa habab kala duwan oo synthetic ah, oo ay ku jiraan falcelinta cyanamide ee leh urea.Waxay leedahay codsiyo dhowr ah oo ku jira warshadaha dawooyinka, gaar ahaan isku-darka daawooyinka ka hortagga kansarka iyo antibiyootiga.Guud ahaan, 2,4-Diamino-6-hydroxypyrimidine waa xarun muhiim ah oo ka heleysa isticmaalka kiimikada iyo daawooyinka kala duwan.
