L-Malic acid

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Magaca Alaabta:L-Malic acid

La mid ah:L-(-)-Malic acid, CP;Butanedioic acid, 2-hydroxy-, (2S)-;pinguosuan;Butanedioicacid,hydroxy-,(S)-;hydroxy-,(S)-Butanedioicacid;l-(ii) -malicacid;L-Gydroxybutanedioicacid;L-Mailcacid

CAS:97-67-6

MF:C4H6O5

MW:134.09

EINECS:202-601-5

Qaybaha Alaabta:Waxyaabaha laga soosaaray dhirta;Aliphatics;MalicAcidSeries;Carboxylic Acids bc0001

Mol File:97-67-6.mol

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Malic acid sifooyinka Kiimikada

barta dhalaalaysa	101-103 °C (Iftiin)
alfa	-2º (c=8.5, H2O)
Barta karkarinta	167.16°C (qiyaasta qallafsan)
cufnaanta	1.60
cadaadiska uumiga	0Pa at 25℃
index refractive	-6.5 ° (C=10, Acetone)
FEMA	2655 \|L-MALIC ACIID
Fp	220 °C
heerkulka kaydinta.	Ku kaydi meel ka hooseysa +30°C.
milmayn	H₂O: 0.5 M at 20 °C, cad, aan midab lahayn
qaab	Budada
midab	Caddaan
Cufis-jiidad gaar ah	1.595 (20/4 ℃)
PH	2.2 (10g/l, H2O, 20℃)
pka	(1) 3.46, (2) 5.10 ( saacada 25 ℃ )
dhaqdhaqaaqa indhaha	[α]20/D 30±2°, c = 5.5% gudaha pyridine
Biyuhu milmayn	milmay
Merck	14,5707
Lambarka JECFA	619
BRN	1723541
InChiKey	BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP	-1.68
Tixraaca XogtaBase ee CAS	97-67-6 (CAS DataBase Tixraaca)
Tixraaca Kiimikada NIST	Butanedioic acid, hydroxy-, (s)-(97-67-6)
Nidaamka Diiwaanka Walxaha EPA	Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)

Macluumaadka Badbaadada

Xeerarka halista	Xi
Bayaanka Khatarta	36/37/38
Bayaanada Badbaadada	26-36-37/39
WGK Germany	3
RTECS	ON7175000
TSCA	Haa
Koodhka HS	29181980

Isticmaalka Malic acid iyo Synthesis

Sharaxaada	L-Malic acid waxay ku dhowdahay ur (mararka qaarkood waa mid daciif ah, ur aan lahayn) oo leh dhadhan asiidh ah.Waa mid aan dhib lahayn.Waxaa lagu diyaarin karaa fuuq-celinta maleic acid;halsano laga bilaabo sonkorta.
Guryaha Kiimikada	L-Malic acid waxay ku dhowdahay ur la'aan (mararka qaarkood waa mid daciif ah, ur daran).Xaruntani waxa ay leedahay dhadhamin, aashito, dhadhan aan dhumuc lahayn.
Guryaha Kiimikada	xal aan midab lahayn oo cad
Dhacdo	Waxay ku dhacdaa dheecaanka maple, tufaaxa, qaraha, babayga, biirka, khamriga canabka, kookaha, darbiga, kiwifruit iyo xidid chicory.
Adeegsada	L-Malic acid waxa loo istcimaalaa cunto lagu daro, α-amino oo la xushay oo ilaalinta reagent ee ka soo jeeda amino acids.Synthon badan oo loogu talagalay diyaarinta xeryahooda chiral oo ay ku jiraan κ-opioid agonists receptor, 1α,25-dihydroxyvitamin D3 analooga, iyo phoslactomycin B.
Adeegsada	isomer-ka si dabiici ah u dhaca waa qaabka L-ka kaas oo laga helay tufaaxa iyo miro iyo dhir kale oo badan.Aashitada α-amino ee la xushay ayaa reagent ka ilaalinaysa amino acids.Synthon badan oo loogu talagalay diyaarinta xeryahooda chiral oo ay ku jiraan κ-opioid rece
Adeegsada	Dhexdhexaad ka ah isku dhafka kiimikada.Wakiilka khiyaamaynta iyo khiyaanada.Walaxda dhadhanka, dhadhamin cusboonaysiinta iyo aashitada cuntada.
Qeexid	ChEBI: Qaab muuqaal ahaan firfircoon oo malic acid leh (S) -habayn.
Diyaarinta	L-Malic acid waxaa lagu diyaarin karaa fuuq-celinta maleic acid;halsano laga bilaabo sonkorta.
Sharaxaada Guud	L-Malic acid waa asiidh organic ah oo inta badan laga helo khamriga.Waxay door muhiim ah ka ciyaartaa xasilloonida microbiological khamriga.
Waxqabadyada Biochem/physiol	L-Malic acid waa qayb ka mid ah dheef-shiid kiimikaadka gacanta.Codsigeeda waxaa laga aqoonsan yahay farmasiyada.Waxay faa'iido u leedahay daaweynta cilladda cagaarshow, waxtar u leh hyper-ammonemia.Waxa loo isticmaalaa qayb ka mid ah faleebada amino acid.L-Malic acid sidoo kale waxay u adeegtaa sidii nanomedicine ee daaweynta xanuunada dareemayaasha maskaxda.TCA (wareegga Krebs) dhexe iyo lammaane ku jira shuttle aspartate malic acid.
Hababka Sifaynta	Crystallize S-malic acid (dhuxusha) laga bilaabo ethyl acetate/ ether xayawaanka (b 55-56o), adoo ilaalinaya heerkulka ka hooseeya 65o.Ama ku milmi adiga oo dib u soo celinaya shan iyo toban qaybood oo ah anhydrous diethyl ether, decant, xooga saar saddex meelood meel mugga oo kristlize 0o, ku celcelin ilaa barta dhalaalka joogtada ah.[Beilstein 3 IV 1123.]